Which LD50 value is the most toxic?

Which LD50 value is the most toxic?

• A. 10 mg/kg
• B. 100mg/kg
• C. 250 mg/kg
• D. 600 mg/kg

Answer: (A)

Toxicity is assessed by LD50, the dose that would kill 50% of a test population. The smaller the LD50 value, the more toxic the substance, because only a tiny amount is needed to reach the lethal threshold. Among the given values, 10 mg/kg is the smallest dose, so it represents the highest toxicity. The other values—100 mg/kg, 250 mg/kg, and 600 mg/kg—require progressively larger doses to achieve the same effect, reflecting lower toxicity. Keep in mind LD50 comes from controlled studies and is a relative measure for comparing substances, not a direct prediction of effects in humans.

Toxicity is assessed by LD50, the dose that would kill 50% of a test population. The smaller the LD50 value, the more toxic the substance, because only a tiny amount is needed to reach the lethal threshold. Among the given values, 10 mg/kg is the smallest dose, so it represents the highest toxicity. The other values—100 mg/kg, 250 mg/kg, and 600 mg/kg—require progressively larger doses to achieve the same effect, reflecting lower toxicity. Keep in mind LD50 comes from controlled studies and is a relative measure for comparing substances, not a direct prediction of effects in humans.